The Villarreal midfielder wished his former team-mate a speedy recovery, insisting he would come back stronger than before.
He was joined by several of the England striker’s team-mates in sending his wishes through social media, along with former club Manchester United.
Danny Welbeck suffered a suspected broken ankle against Sporting Libson in Europa League
In the post, Cazorla said: ‘Get Well soon my friend. These are the worst things in football but I know you are strong and you will come back, you deserve the best My man.’
Welbeck sustained the injury when landing heavily on his ankle after challenging for a header in the 30th minute.
He was replaced by Pierre-Emerick Aubameyang and carried from the pitch on a stretcher after receiving treatment on the pitch fr several minutes.
Welbeck’s England and former Manchester United team-mate Jesse Lingard also sent his best wishes through Twitter, saying ‘Get well soon brother’.
Arsenal team-mates Alexandre Lacazette and Mesut Ozil, who were both rested for the European clash, were quick to offer their thoughts to their stricken team-mate.
Despite receiving limited playing time in the Premier League this season, Welbeck had registered five goals in 12 games for the Gunners.
He had also been named in England’s squad for the upcoming friendly against the USA and Nations League clash with Croatia.
Welbeck has a history of serious injuries at Arsenal, having missed England’s Euro 2016 campaign with a meniscus tear just months after recovering from another serious knee injury.
The striker was carried from the pitch on a stretcher after being given an oxygen mask